Matt Claydon#
Matt Claydon
Senior Research Associate
My interest in neuroscience started during my undergraduate degree at UCL, and that was furthered during my MSc in molecular neuroscience at the University of Bristol. During my MSc I got a taste for research and went on to complete a PhD investigating the effects of circadian disruption and steroid treatment using brain slice electrophysiology. I have joined Jack’s lab in 2024 as a postdoc and am now investigating risk genes associated with schizophrenia.
Research:#
My research in the Mellor lab will utilise two-photon imaging of dendritic calcium, combined with whole-cell electrophysiology, to assess the convergent and divergent changes in synaptic integration and physiological properties that may arise from several high-risk genetic mutations associated with schizophrenia. I use a combination of acute brain slices and cultured organotypic human brain slices.
Outside of the lab
I love powerlifting, though am yet to compete…
I love getting out in nature, trail running, completed my first ultra in October ‘23!
Cooking (and eating)
Live music and board games
Watching football & rugby
Publications:#
Circadian regulation of hippocampal function is disrupted with corticosteroid treatment
Matthew T Birnie, Matthew D B Claydon, Oliver R Troy, Becky L Conway-Campbell
Proceedings of the National Academy of Sciences 2023 (article)
The glucocorticoid-mediated genomic stress response
Matthew D B Claydon, Becky L Conway-Campbellr
Current Opinion in Endocrine and Metabolic Research, 2022 (article)
Pharmacological characterizations of the ‘legal high’ fluorolintane and isomers
Jason Wallach, Tristan Colestock, Julià Agramunt, Matt Claydon, Michael Dybek, Nathalie Filemban, Muhammad Chatha, Adam L. Halberstadt, Adam L. Halberstadt, Simon Brandt, David Lodge, Zuner A Bortolotto, Adeboye Adejare
European Journal of Pharmacology, 2019 (article)